IL15 and T-cell Stemness in T-cell–Based Cancer Immunotherapy

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IL15 and T-cell Stemness in T-cell-Based Cancer Immunotherapy.

Preclinical models revealed that the immune system can mediate rejection of established tumors, but direct evidence in humans has been limited to largely immunogenic tumors, such as melanoma. The recent success of immune checkpoint inhibitors and adoptive T-cell transfer immunotherapy in clinical trials has instilled new hope for the use of T-cell immunotherapy in the treatment of cancer. IL15,...

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ژورنال

عنوان ژورنال: Cancer Research

سال: 2015

ISSN: 0008-5472,1538-7445

DOI: 10.1158/0008-5472.can-15-1498